Robustness measures for cell type classification in single-cell RNA-seq datasets of kidney organoids
Background: Induced pluripotent stem cell (iPSC)-derived kidney organoids hold great promise for disease modeling, drug screening, and regenerative medicine. However, since these organoids are synthetic constructs, it is essential to evaluate how faithfully their constituent cell populations recapitulate the corresponding cell types in the native kidney. Single-cell transcriptomic label-transfer…
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