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Cardinals vs. 49ers history: Arizona struggling in recent meetings

The Cardinals have lost six of their last eight games against the 49ers.

The Arizona Cardinals are set to take on the San Francisco 49ers on Sunday in a road game, but their recent history against the 49ers has been a struggle. Since last season, the Cardinals have lost both meetings with the 49ers and have a 2-6 record in their last eight matchups. The 49ers lead the all-time series between the two teams with a 38-31 record.

The Cardinals did experience an 8-0 winning streak from 2015-2018, but the 49ers have claimed nine of the last 14 meetings since then. Notably, 49ers quarterback Brock Purdy boasts a 5-1 record in six starts against the Cardinals during his career. In the most recent season, backup quarterback Mac Jones managed to defeat the Cardinals. The only other notable victory for the Cardinals in recent times came in 2024, when Joshua Dobbs started for the 49ers.

For the Cardinals' first-year head coach, Mike LaFleur, this matchup presents an opportunity to face his mentor, Kyler Shanahan. LaFleur served as an assistant coach for the 49ers from 2017-2020 under Shanahan. Despite recent struggles, the Cardinals have managed to secure six victories and five losses at Levi's Stadium since its opening in 2014. For more Cardinals and NFL coverage, listeners can tune in to the Rise Up, See Red podcast hosted by Cards Wire's Jess Root.

Written by urgent.news from Yahoo Sports's reporting — not their text. Machine-written — may contain errors; check the original before relying on it.

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