9 new movies and shows to stream this weekend on Netflix, Prime Video and more (Sept. 25-27)

This weekend, streaming enthusiasts have a plethora of options to choose from across various platforms, including Netflix, Prime Video, Hulu, NBC, Peacock, and FX. From comedy and drama to horror and crime, there's something for every taste.

For those in the mood for a comedy, "Brothers" on Apple TV offers a unique twist on the buddy comedy genre. Matthew McConaughey and Woody Harrelson play exaggerated versions of themselves as they investigate whether they may share a biological father, adding to the hilarity. Meanwhile, on Prime Video, the romantic comedy "The Love Hypothesis" explores the concept of fake dating and the growing feelings between two scientists. With a runtime of 1 hour and 52 minutes, this film promises a delightful escape.

"American Horror Story: 13" on Hulu brings back beloved characters and nightmares from the anthology series. With Jessica Lange, Sarah Paulson, Evan Peters, and Emma Roberts reprising their roles, this 42-minute episode offers a nostalgic and eerie experience.

For fans of medical dramas, "Best Medicine" season 2 on Fox presents a new season following Dr. Martin Best, played by Josh Charles. As his medical license remains under scrutiny and his blood phobia poses a challenge, the series adds a mermaid to the mix, ensuring a thrilling and engaging watch.

"Line of Fire" on Peacock introduces viewers to the Hollingsworth family, all working in federal law enforcement. With stories revolving around a routine murder investigation and a conspiracy targeting agents, this crime drama provides a perfect mix of family dynamics and suspense.

Finally, "Saturday Night Live" season 52 returns on NBC, kicking off with Jalen Brunson hosting his first episode. The show features a fresh roster of cast members, including new Weekend Update anchors Colin Jost and Michael Che, and brings back the beloved cast such as Kenan Thompson. This comedy extravaganza promises plenty of laughs and surprises for fans of the iconic sketch comedy show.