Multi-vector retrieval enables residue-resolved prediction of protein partners by ColBERT-PPI

Protein-protein interactions (PPIs) are central to biological processes, making the identification of both interacting partners and their binding sites important for understanding molecular function and guiding therapeutic discovery. However, connecting large-scale partner prediction to residue-level interaction evidence remains challenging. Here we present ColBERT-PPI, a structure-aware…

biorxiv.org ·1d ago

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