A Statistical Guideline for Analyzing Repeated-Measures Proteomics Data

Mass spectrometry-based proteomics increasingly supports study designs with repeated measurements, such as longitudinal sampling and spatial tissue profiling. These designs offer rich biological insights but introduce statistical challenges due to within-subject correlations and variance heterogeneity across time points or anatomical locations. Despite the growing use, best practices for…

biorxiv.org ·1d ago

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