College football picks: USC set to knock off Ducks as teams enter meat of season in prove-it mode

winnipegfreepress.com ·2h ago

Week 4 of college football season is a proving ground for top-ranked teams, with several high-profile matchups set to reveal their true abilities. After a series of blowouts and a few thrilling opening games, there is significant interest in how these teams will perform in their next challenges. The article highlights a particularly intriguing clash between No. 20 Oregon and No. 12 Southern California, citing Oregon's recent loss to Oklahoma State and USC's defensive challenges under new coordinator Gary Patterson.

The article also explores other matchups where the outcome could significantly impact the season, such as Mississippi validating its win over LSU, Iowa's offensive improvement, Penn State's performance against Wisconsin, and Florida's potential to live up to its ranking.

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