Variation in enhancer activity across brain regions defines neurological disease risk and shapes cellular pathology
Genetic variants associated with neurological traits are enriched in enhancers active in neurons. However, there are many types of neurons with varying functions across the brain, making it difficult to pinpoint insights into disease pathology. We set out to investigate whether cell type and brain region specificity of transcriptional enhancers could reveal new insights into the cellular…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
