Repeated cocaine reorganizes striatal ensembles along the ventral-dorsal axis
Drugs of abuse produce lasting adaptations in the striatum. A prominent theory holds that the early reinforcing effects of cocaine preferentially engage the ventral striatum, and repeated cocaine use recruits dorsal striatal systems associated with habitual drug-related behavior. However, this transition has largely been conceptualized on the population level, obscuring how it is implemented…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
