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Large-scale esophageal cancer screening through noncontrast computed tomography and artificial intelligence

Nature Medicine, Published online: 22 September 2026; doi:10.1038/s41591-026-04656-4 In a large-scale study, a new tool called Esophageal AI-Guided malignant Lesion Evaluation uses artificial intelligence to enhance esophageal cancer detection through noncontrast computed tomography, achieving high sensitivity and specificity across diverse settings.

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