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Blood proteomics of menopause map to brain aging and dementia risk

Nature Medicine, Published online: 22 September 2026; doi:10.1038/s41591-026-04648-4 Leveraging proteomic data from nearly 15,000 women across several cohorts, this study found that menopause is associated with hormone-linked molecular changes that correlate with poorer cognitive outcomes later in life and the molecular signatures identified might inform selection of therapeutic targets to…

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