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Aged-associated changes in active YAP staining during impaired skin wound healing in aged mice and delayed wound closure in ICE mice

Aging is associated with impaired skin wound healing, but the molecular mechanisms underlying this decline remain incompletely understood. In particular, how aging affects the temporal regulation of mechanosensitive signaling during tissue repair is poorly understood. In this study, we investigated age-associated changes in cutaneous wound healing, with a focus on Yes-associated protein…

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