Development of a novel loop-mediated isothermal amplification (LAMP) assay for Balamuthia mandrillaris
Balamuthia mandrillaris is a free-living amoeba that can cause cutaneous skin lesions, systemic disease, and a severe life-threatening CNS infection, Balamuthia amoebic encephalitis (BAE), which has a high mortality rate (~92%). The current diagnostic methods for B. mandrillaris have many limitations including the long detection time, low sensitivity, and specific diagnostic tests only available…
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