Stepwise reorganization of chromosome conformation and nuclear organization during stem cell differentiation
Nuclear organization is a fundamental feature of cell identity and cell fate determination. Compared with differentiated cells, pluripotent stem cells exhibit markedly distinct nuclear architecture at multiple levels, including chromosome folding, lamina association, histone modification landscapes and nuclear body organization. Although individual aspects of this reorganization have been…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
