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NIX-associated mitochondrial remodeling contributes to esophageal epithelial differentiation

Mitochondria are increasingly recognized as regulators of cellular differentiation, but their role in esophageal epithelial homeostasis remains poorly understood. Here, we investigated mitochondrial remodeling during esophageal epithelial differentiation and whether mitochondrial depletion contributes to the acquisition of the differentiated phenotype. Mitochondrial abundance was assessed across…

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