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Mechanical coupling narrows an epithelial colony before it reaches a bottleneck

A colony migrating into a passage narrower than itself but wider than individuals must adapt its density distribution to pass. Powders, colloids and crowds driven through such an opening jam, since contact interactions provide no pathway for constituents to respond to the constriction before reaching it. Exploring whether a cohesive living tissue can reorganize in advance, we image MDCK…

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