Distinct RNA-RNA spatial interaction sub-networks of transcription factors in hepatic cells
We applied the latest RIC-seq technology to study the RNA-RNA interactions in human liver HepG2 cells. Integrating ChIP-seq data with the RIC-seq data, we clas-sified vari ous transcription factors (TFs) into two distinct clusters based on the in-teraction enrichment scores of the uaRNA (RNA transcribed in promoter regions) and eRNA (RNA tran scribed in enhancer regions) potentially transcribed…
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