Curved by Design: Applying Microfluidic Principles for Nonplanar and Planar Suspended Tissue Patterning to the Development of Bladder Models with Tunable Mechanics
Cells in vivo exist in a complex environment where they receive chemical and physical cues from neighboring cells and the extracellular matrix. Suspended, three dimensional (3D) cell culture enables the study of mechanical signals in a controlled in vitro setting where cells can exert forces on the extracellular matrix, and mechanical stimulation can be externally applied. In addition to…
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