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Characterizing Individual and Population-Level Heterogeneity in Infant BMI Trajectories Using Flexible and Functional Modeling Approaches

Infant body mass index (BMI) follows a rapid and nonlinear trajectory, yet substantial inter-individual variation complicates accurate characterization of growth dynamics. Here we systematically compared individual- and group-based approaches for modeling longitudinal BMI trajectories in 2,114 healthy infants. Among linear spline, natural cubic spline and fractional polynomial mixed-effects…

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