A putative cis-regulatory element near Shox2 in the jerboa genome (Jaculus jaculus) is not sufficient to alter mouse limb bone lengths
Vertebrate limb bones grow at different rates within and between species to achieve a striking variety of proportions and functions. However, most coding mutations that alter bone growth in mice and humans affect the entire skeleton, pointing to cis-regulatory modularity as the primary mechanism to diversify proportion. In a search for causative loci, we previously identified 1,755…
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