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Prenatal Inflammation as a Determinant of Long-Term Cardiovascular Risk: Evidence from a Murine Model

Background Intrauterine inflammation is associated with increased lifetime cardiovascular disease (CVD) risk in offspring, yet long-term molecular mechanisms remain underexplored. We investigated the lasting cardiometabolic, hemodynamic, and vascular effects of prenatal inflammatory exposure in adult offspring using a mouse model. Methods On day 15 of gestation, pregnant CD-1 mice were randomized…

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