NFL Week 2 expert picks, score predictions: Lions at Bills
Detroit Lions vs. Buffalo Bills NFL Week 2 expert picks made by the Pride of Detroit staff.
The Detroit Lions faced their first road game of the 2026 season, traveling to Highmark Stadium to take on the Buffalo Bills in their home opener. Lions head coach Dan Campbell praised Bills quarterback Joe Brady, calling him a "catalyst" for the team. Campbell also highlighted the offensive line, defensive line, and running back Melvin Gordon as key strengths for the Bills.
The Lions were aware of the challenge they faced, noting that the Bills have shown to be aggressive on special teams and that it will be an exciting atmosphere at their new stadium.
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