MMAD-Risk: Multivariate Mixed Survival Analysis for the Prediction of Age-Dependent Disease Risks from Plasma Proteomes
Motivation: Multivariate survival analysis with hundreds of correlated outcomes is computationally challenging. Established approaches either ignore correlations between response variables, rely on black-box deep learning or are limited to small-scale outcomes. Results: We introduce MMAD-Risk, a novel multivariate mixed accelerated failure time (AFT) model that enables scalable analysis of…
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