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How a team of AIs discovered a promising lung-cancer drug

Nature, Published online: 17 September 2026; doi:10.1038/d41586-026-02954-y Researchers developed a ‘virtual biotech’ made up of as many as 37,000 agents reporting to an 'chief scientist'.

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The system lives in your files, not your prompts

AI Harness Engineering · Essay One · derek wang (derekwang85) Ask a senior engineer where "the system" lives and they'll point at the code, or the org chart.

  • System resides in files, not prompts
  • Five-layer pyramid of constraints guides output
  • Constraints are non-negotiable rules for model

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