Urgent.News

What's breaking now, across thousands of outlets.

AI

From Prompt to Pipeline: A Comparative Evaluation of Large Language Model Coding Agents for Reproducible Bioinformatics Pipeline Construction

Agentic coding systems are increasingly presented as a way to reduce the engineering burden of scientific software development. Bioinformatics is a strong test case for this claim because useful pipelines must combine domain-specific analysis choices, command-line software, sample metadata, workflow orchestration, container or HPC execution, and interpretable quality-control reporting. We…

We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.

Read the original at biorxiv.org →

More in AI

The system lives in your files, not your prompts

AI Harness Engineering · Essay One · derek wang (derekwang85) Ask a senior engineer where "the system" lives and they'll point at the code, or the org chart.

  • System resides in files, not prompts
  • Five-layer pyramid of constraints guides output
  • Constraints are non-negotiable rules for model

More from Thursday 17 September →