Precision cooling assists electrical stimulation: Breaking selectivity barriers in nerve control
Peripheral neuromodulation can relieve pain through sensory activation or conduction block. However, electrical stimulation of mixed nerves couples these intended effects to unwanted neural activity. Here we demonstrate local cooling can separate targeted from off-target neural activity. In the rat sciatic nerve, precooling reduced the onset response to kilohertz-frequency stimulation by about…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
