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J-domain proteins stimulate PKL-mediated chromatin compaction at H3K4-hypomethylated genomic loci

Chromatin accessibility varies widely across distinct genomic regions in eukaryotes, yet the mechanisms governing these differential patterns remain poorly understood. Here, we identify a subfamily of functionally redundant J-domain proteins (JDPs) that assemble into a protein complex with PICKLE (PKL), an evolutionarily conserved CHD3-type chromatin remodeler, in Arabidopsis thaliana. JDPs are…

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NASA Ames Stars of the Month: September 2026

The NASA Ames Science Directorate recognizes the outstanding contributions of (pictured left to right) Steve Ormsby, Aphrodite Kostakis, Alejando Borlaff, Sarah Nickerson, Martina Caussi, Keiko…

NASA Ames Stars of the Month: September 2026

The NASA Ames Science Directorate recognizes the outstanding contributions of (pictured left to right) Steve Ormsby, Aphrodite Kostakis, Alejando Borlaff, Sarah Nickerson, Martina Caussi, Keiko…

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