Incomplete references leave bulk deconvolution targets non-identifiable, but identification has a computable precision price
Background: Reference-based deconvolution estimates cell-type proportions from bulk profiles. Incomplete references are its dominant error source, yet every current remedy ends in a point estimate. We separate the operator provenance that reproduces an estimate from the information and precision that identify its target. Results: Crossing two operator histories at one reduced reference shows the…
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