Insight into the mechanism of molecular interactions of the NDM metallo-beta-lactamase and cyclic boronate inhibition by molecular docking and molecular dynamics simulations
The spread and evolution of antimicrobial resistance (AMR) pose significant threats to public health, food safety, and sustainable development. Metallo bea lactamases (MBLs), a class of carbapenemases that hydrolyze carbapenems, often considered last resort antibiotics, are of particular concern and underscore the urgent need to develop effective inhibitors. Recent advancements in bicyclic…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
