Doublecortin mutation disrupts lattice-dependent proximity to reveal cytoskeletal networks in developing neurons
Doublecortin (DCX) is a microtubule-associated protein (MAP) required for neuronal migration and cortical development. However, DCX is not sufficient to direct these processes on its own. Instead, nucleokinesis, growth cone advancement, collateral branching, and polarity depend on the coordination of different MAPs and cytoskeletal proteins, including DCX, to define distinct polymer properties…
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