Resolving context-specific protein-protein interactomes forbiological discovery and therapeutic target prioritisation
Protein function is shaped by cellular context, yet most protein representations and interaction maps remain context-agnostic. Here we present ProtScape, a multiscale graph-learning framework integrating global protein interactions, cell-type gene expression and protein language models to learn context-specific representations and infer interactomes across more than 200 cell types. ProtScape…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
