LIGER2: Scalable Single-Cell Integration with On-Disk Datasets
Correcting batch effects and integrating single-cell sequencing datasets has been a crucial step in large-scale biological studies. Many methods have been published for this task, and excel in various scenarios. Our previous work, LIGER, leveraging integrative non-negative matrix factorization (iNMF), stands out in providing an interpretable low-dimensional representation. To adapt to the modern…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.