NFL Week 1 expert picks: Moneyline predictions, against the spread
Our staff of NFL experts make their picks and predictions for every Week 1 game of the 2026 season.
Week 1 of the 2022 NFL season brought an array of high-stakes matchups across the United States and internationally. On Thursday night, the San Francisco 49ers took on the Los Angeles Chargers in a crucial NFC West game during their Australian tour. On Sunday Night Football, the Dallas Cowboys faced off against the New York Giants, while the week concluded with a clash between the Denver Broncos and Kansas City Chiefs, both aiming for AFC Super Bowl supremacy.
Other notable games included the NFC North encounter between the Packers and Vikings, as well as the Baltimore showdown between the Ravens and Colts. As the league's premier staff, our analysts are tasked with providing expert picks for every Week 1 game, offering insights and potential bragging rights within the team. We encourage fans to share their own predictions in the comments section below, with all picks expected to be posted on our website.
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