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Naegleria amoebae seek confinement and crawl persistently through narrow spaces

Proceedings of the National Academy of Sciences, Volume 123, Issue 38, September 2026. SignificanceThe “brain-eating amoeba”Naegleria fowlericauses a devastating brain infection with a ~95% fatality rate, yet how these normally harmless pond-dwellers invade the human brain remains mysterious. Using the model speciesN. gruberi, we show ...

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