Integrating Narrow-Window DIA with AI-Powered Search Enables Deep and Reliable Functional Proteomics
Narrow-window data-independent acquisition (nDIA) is emerging as a powerful technique for bottom-up proteomics. Here, we systematically benchmarked nDIA, wide-window DIA (wDIA), narrow-window data-dependent acquisition (nDDA), and wide-window DDA (wDDA) for rapid, single-shot proteomic analysis. For data processing, we introduced Tesorai Search, a new search engine leveraging a large pre-trained…
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