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As China embraces AI, only 24% of US pharma execs bet on it for drug-making

Pharmaceutical companies have embraced artificial intelligence in drug research almost universally, yet few company executives expect AI to actually make drugs succeed, according to a Citi survey released on Tuesday. “The biggest risk to the AI-powered drug discovery thesis is not that AI fails to accelerate discovery,” said John Yung, head of Asia healthcare research at the US investment bank.…

As China embraces AI, only 24% of US pharma execs bet on it for drug-making

A recent Citi survey reveals that while many US pharmaceutical executives are optimistic about AI's role in drug discovery, only a quarter expect it to significantly improve the likelihood of developing successful drugs. The biggest risk to AI-powered drug discovery is not its acceleration of discovery, but rather whether that speed translates into better drugs and higher success probabilities.

Currently, 72% of surveyed executives have either "scaled" or "fully scaled" AI across research and development. However, only 24% anticipate AI delivering a meaningful boost in drug success probability, with 56% predicting only a moderate improvement. Human biology, clinical judgment, and execution are seen as persistent bottlenecks regardless of AI deployment.

Early-stage discovery, particularly targeting identification and validation, is seen as the area where AI can yield the most success rate improvements, followed by lead optimization and hit identification/screening. Executives anticipate a double-digit rise in AI-related R&D spending over the next year. Chinese companies like HitGen and Xtalpi are already profitable and could see earnings accelerate as demand for their AI-powered solutions grows.

However, Chinese AI drug discovery firms trade at a significantly lower price-to-sales ratio compared to their US counterparts, indicating a potential undervaluation.

Written by urgent.news from Reuters Business via SCMP's reporting — not their text. Machine-written — may contain errors; check the original before relying on it.

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Read the original at scmp.com →

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