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New review highlights promise of intra-arterial stem cell therapy to improve stroke recovery

Researchers from the University of Miami Miller School of Medicine and collaborating institutions have published a comprehensive review examining the rapidly evolving field of intra-arterial stem cell therapy for ischemic stroke, highlighting its potential to improve recovery for patients who continue to face disability despite major advances in stroke treatment.

New review highlights promise of intra-arterial stem cell therapy to improve stroke recovery

A new review highlights the potential of intra-arterial stem cell therapy in improving stroke recovery for patients who continue to face disability despite major advances in stroke treatment. Published in the journal Stroke: Vascular and Interventional Neurology, the review, titled "Progress in Intra-arterial Stem Cell Therapy for Ischemic Stroke—A Review," examines decades of preclinical and clinical research and outlines a roadmap for translating regenerative therapies from the laboratory to the bedside.

Ischemic stroke, caused by a clot cutting off blood supply to the brain, remains a leading cause of death and long-term disability worldwide. While clot-busting medications and mechanical thrombectomy have transformed care for acute ischemic stroke, many patients still experience significant neurological deficits. The authors argue that intra-arterial stem cell therapy, delivered directly into the brain's circulation via minimally invasive catheter angiographic techniques, may complement existing treatments by promoting repair, reducing inflammation, and enhancing recovery.

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