TheCellVision.org repository: expansion with high-content cell imaging projects on eukaryotic intracellular organization and DUB biology
High-content cell imaging approaches enable the systematic characterization of cellular function through the acquisition of multimodal information from large cohorts of live single cells. Yet, due to their scale and complexity, data acquired via such approaches are often challenging to meaningfully share across laboratories and effectively use for independent studies. Since its inception, the…
TheCellVision.org repository has undergone its third major update, expanding the collection with data from two significant single-cell phenomics projects. The Intracellular Organization Dynamics project focuses on mapping the morphological changes in 21 major subcellular structures in live yeast cells caused by the inhibition of essential genes.
Meanwhile, the DUB Biology project investigates alterations in the concentration and localization of the budding yeast proteome in mutants of crucial deubiquitination enzymes (DUBs). These additions bring the repository to six complementary high-content imaging projects, all exploring the dynamics of intracellular organization and the proteome in response to cellular state changes and genetic or environmental disruptions.
Written by urgent.news from bioRxiv's reporting — not their text. Machine-written — may contain errors; check the original before relying on it.
