Men with low or high testosterone may have a higher risk of irregular heartbeat, review indicates
Men with either low or high testosterone levels may face a higher risk of atrial fibrillation, highlighting the need for personalized testosterone treatment, according to a review of existing evidence on testosterone and heart health published in the Journal of the Endocrine Society.
A recent review of scientific evidence suggests that both low and high testosterone levels may increase the risk of atrial fibrillation, a type of irregular heartbeat. Testosterone replacement therapy, commonly used for middle-aged and older men, may pose additional risks if not carefully monitored. The study, published in the Journal of the Endocrine Society, indicates that the optimal testosterone level for reducing atrial fibrillation risk is somewhere in the middle of the normal range, approximately 350-550 ng/dL.
This finding is based on both large population studies and recent laboratory research showing that both low and high testosterone levels disrupt heart cells in different ways. The researchers emphasize the need for personalized treatment, restoring testosterone to this mid-range level rather than pushing it to the higher end, and implementing structured monitoring.
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