Genome-scale label-free imaging reveals cellular physiology encoded in bacterial collective architecture
DNA sequencing unified microbial genotyping into a single, comprehensive readout, yet phenotyping remains a slow and fragmented endeavor. Here, we introduce Microbial Phenotyping Using Low-magnification Label-free Imaging (PULLI), a computer vision platform that extracts microcolony and population-level phenotypes from brightfield timelapses of liquid culture growth. Using PULLI, we screened a…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
