A Scalable Cross-Modal Workflow for Linking In Vivo Neural Activity to Neuronal Cell Types via Spatial Gene Profiling
A central challenge in systems neuroscience research is to elucidate how distinct neuronal cell types coordinate to produce complex behaviors: an endeavor that requires linking their molecular identity, connectivity and activity patterns in behaving animals. Recent advances in single-cell RNA sequencing and spatial transcriptomics have revealed remarkable molecular diversity among neurons.…
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