EASI-PASS: An accessible pipeline for linking functional imaging and mRNA profiling

We developed EASI-PASS, a reliable, high-throughput method for estimating the molecular identity of functionally characterized cells by merging live imaging with subsequent fixed-tissue imaging using conventional microscopes. Our method matches the shapes and locations of thousands of densely imaged cells between large (>1 mm2) functional images and a thick, expanded, and cleared EASI-FISH tissue…

biorxiv.org ·23h ago

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Bright people know more about wine: How higher intelligence is reflected in deep domain knowledge

Intelligent people tend to perform better at school and at work, as numerous studies have shown. But what happens in domains where incentives such as good grades or financial rewards don't apply and where socioeconomic status is not a significant factor? Wine knowledge is a case in point.

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Even as the scientific community has reached a broad consensus that infectious pathogens, such as viruses, can spread through virus-laden aerosols, one fundamental challenge remains: How can scientific evidence be transformed into public understanding—and ultimately into meaningful action for effective airborne disease control and…

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EASI-PASS: An accessible pipeline for linking functional imaging and mRNA profiling

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