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Research updates, August 25

Another observational study found more evidence of endothelial dysfunction in Long COVID. German researchers evaluated the eyes of 102 people with Long COVID, comparing them to 102 people “recovered” from COVID-19, as well as controls. The post Research updates, August 25 first appeared on The Sick Times .

Research updates, August 25

Another observational study has revealed additional evidence of endothelial dysfunction in individuals suffering from Long COVID. Researchers in Germany examined the eyes of 102 people with Long COVID, comparing them to 102 individuals who had recovered from COVID-19 and a control group. Utilizing a non-invasive technique called retinal vessel analysis, the study detected abnormalities in the blood vessels of those with Long COVID.

The researchers noted the abnormalities were more pronounced in participants who also met the criteria for myalgic encephalomyelitis (ME). Furthermore, they discovered that those with these abnormalities exhibited worse neurocognitive symptoms. Additionally, a small clinical trial published in the British Journal of Biomedical Science found that a probiotic formula called VSL#3 helped alleviate fatigue in individuals with Long COVID.

The trial involved 23 participants who consumed two sachets of the formula daily for 28 days or a placebo. Italian researchers utilized the Chalder Fatigue Scale as a primary endpoint, discovering that the formula significantly reduced fatigue compared to the placebo. An exploratory biological analysis revealed that the formula reduced certain pro-inflammatory and immune-related cytokines.

The researchers concluded that further research is needed to explore treatments targeting the microbiome for Long COVID, particularly with larger sample sizes.

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