Can you slow the aging process? Study reveals which interventions might help
When Raghav Sehgal arrived at Yale as a graduate student several years ago, he wanted to explore the use of powerful computer science tools in cancer research. With an engineering background and a computational biology startup already under his belt, he was well prepared.
A recent study has identified specific interventions that may slow the aging process, according to research conducted by Raghav Sehgal, an associate research scientist in psychiatry at Yale School of Medicine. Sehgal's team utilized a new class of DNA-based blood tests, known as epigenetic clocks, to measure the effects of various interventions on biological age.
They discovered that diet and exercise, as well as certain drug treatments like metformin, semaglutide, and anti-TNF therapies, consistently decreased epigenetic age. Lifestyle interventions, including a healthy diet and regular physical activity, were found to have the most significant impact, followed by pharmacological interventions.
In contrast, over-the-counter supplements and some medical procedures showed little effect on slowing aging. The researchers emphasize the need for further clinical validation to determine if these biomarkers can reliably predict long-term health outcomes.
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