This yeast supplement may boost cancer-fighting immunity

Researchers at Trinity College Dublin and University College Dublin discovered that a yeast-based supplement called yeast beta-glucan can enhance immune cells in mice, potentially boosting their cancer-fighting abilities. In experiments with obese mice, the supplement altered immune cell development and produced stronger anti-tumor responses.

Obesity can negatively impact immune function, making it harder for the body to respond to tumors effectively. The study, published in Cell Reports, suggests that a yeast-based supplement may help restore lost immune activity in obese individuals. Lead researcher Dr. Anna Ledwith found that 4-12 weeks of yeast beta-glucan supplementation in mice's diets led to enhanced immune responses against colorectal, skin, and breast cancer.

The researchers also noted that the supplement could counteract immune dysfunction caused by obesity, even after weight loss. Professor Helen Roche, a study co-author, emphasized that this is the first time dietary delivery of yeast beta-glucan has been shown to induce trained immunity through bone marrow stem cell reprogramming.

Previous research required injections. The supplement's safety and widespread availability make it a promising candidate for future clinical trials in humans, potentially complementing existing cancer treatments and improving vaccine responses in immunocompromised populations.