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How to Connect Python to a SQL Database (Straight Into a DataFrame)

By Michael Nocito , data analyst · Published August 8, 2026 By the end of this page you will run a SQL query from Python and get back a pandas DataFrame with real column names, ready to chart or…

  • Use pd.readsql() to connect Python to SQL and load results into DataFrame
  • Establish connection with sqlite3 module, built-in to Python
  • Safely insert variable data using placeholders and params= argument

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