Synovitis Confirmed as Prognostic in Hand Osteoarthritis, Regardless of Subtype
(MedPage Today) -- Patients with osteoarthritis (OA) of the hand face the same risk of structural progression when synovitis is present in the first carpometacarpal (CMC1) joint versus the interphalangeal joints, results of a prospective cohort...
A recent study has found that synovitis in hand osteoarthritis (OA) plays an equivalent prognostic role, regardless of whether it occurs in the first carpometacarpal (CMC1) joint or the interphalangeal joints. The prospective cohort study involved 201 patients with hand OA, who were followed for an average of 3.4 years. Those with high-grade synovitis in the CMC1 joint at the beginning of the study had 9.3 times higher odds of clinically significant radiographic progression compared to patients without synovitis, whereas the odds ratio for synovitis in predominantly interphalangeal OA was 23.4 (95% CI 10.4-52.9).
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