The extracellular matrix regulates tissue mechanics to enable cyclic lymph node remodelling and sustained immunity
Tissue shape and function are defined by the mechanical interactions of cellular and extracellular components. Lymph nodes cyclically remodel in response to immune challenges whilst preserving essential stromal structures. However, the relative contributions of the fibroblastic reticular stromal cell network and the ensheathed extracellular matrix, remain undefined. We quantified the contribution…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
