TGF-β2-induced Snail-mediated EndMT signaling relies on both Smad-dependent and independent pathways
Endothelial-to-mesenchymal transition (EndMT) has become a central mechanism in developmental biology, fibrosis, vascular disease, and cancer. We previously reported on an integrated signaling model in which TGF-{beta}2 induces EndMT through coordinated activation of Smad-dependent and Smad-independent signaling pathways converging on Snail, while GSK-3{beta} regulates Snail activity. We…
We haven't written up this one. bioRxiv has the full story — the link below goes straight to it.
