Attaining a healthy weight range linked to lower risk of type 1 diabetes progression
A Baylor College of Medicine-led team found that moving into a normal weight range was associated with about half the risk of progressing to clinical type 1 diabetes (T1D), particularly in youth. This observational study, published in Diabetes Care, was conducted in individuals with early signs of type 1 diabetes.
A research study led by Baylor College of Medicine found that moving from overweight or obese to a normal body mass index (BMI) is linked with a 48% lower risk of progressing to clinical type 1 diabetes (T1D), especially in youth. Conducted on 833 participants in the TrialNet study, the research followed individuals with early signs of T1D and overweight or obesity for about four years.
The strongest associations were found in children and teens, particularly boys under 12 and girls aged 12-17. The study did not establish causation, as it is observational, but it provides strong evidence for further research into whether promoting a healthy BMI can alter T1D progression.
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