Kinetochore diversification in Naegleria reveals plasticity in the kinetochore-microtubule interface
The kinetochore--the molecular machine that couples chromosomes to spindle microtubules--performs an essential, tightly regulated function, yet varies dramatically across eukaryotes. Microtubules are critical binding partners for the kinetochore, yet whether or how they influence or constrain kinetochore evolution is unclear. To address this problem, we turned to the amoeba Naegleria, which…
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